So that degeneration of the cells will now produce sort of like a scar called a plaque.

So these plaques can affect multiple parts of the brain.

And because it can affect multiple parts of the brain, it can produce multiple symptoms and multitude of problems.

And over a period of time, these plaques will accumulate in the brain eventually producing disability.

So that is the concern about multiple sclerosis because it's an autoimmune disease with chronic inflammation and a tendency for remissions and exacerbations.

So they keep on getting these attacks unless we treat that with some disease modifying agents.